human ARHGAP26 shRNA silencing Adenovirus

Name 
Ad-h-ARHGAP26-shRNA
Cat No 
shADV-201324
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ARHGAP26.

shADV-201324
Ad-h-ARHGAP26-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ARHGAP26 (Rho GTPase activating protein 26). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); oligophrenin-1-like protein; OPHN1L; OPHN1L1; rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
Description (eCommerce)
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. GTPase regulator associated with focal adhesion kinase (GRAF) is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc4 [taken from NCBI Entrez Gene (Gene ID: 23092)].
Description (Vector)
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
23092
Gene Name (eCommerce)
Rho GTPase activating protein 26
Gene Name (Vector)
Rho GTPase activating protein 26
Gene Symbol
ARHGAP26
HGNC ID
HGNC:17073
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2280
ORF Size (bp)
2280 bp
Protein Name (eCommerce)
Rho GTPase-activating protein 26
RefSeq ID
NM_015071
RefSeq Synonyms
NM_015071, NM_001135608, BC068555,
Research Areas
Cancer,Cytoskeleton,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. GTPase regulator associated with focal adhesion kinase (GRAF) is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc4 [taken from NCBI Entrez Gene (Gene ID: 23092)].
UniGene ID
Hs.654668
UniProt ID (eCommerce)
Q9UNA1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.