human ARG2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ARG2.
shADV-201298
Ad-h-ARG2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ARG2 (arginase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
Gene ID
384
Gene Name (Vector)
arginase 2
Gene Symbol
ARG2
HGNC ID
HGNC:664
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_001172
RefSeq Synonyms
NM_001172, BC029050, BC008464, BC001350,
Species
human
UniGene ID
Hs.708024
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.