human AQP3 shRNA silencing Adenovirus

Name
Ad-h-AQP3-shRNA

Cat No
shADV-201238

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human AQP3.

shADV-201238

Ad-h-AQP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AQP3 (aquaporin 3 (Gill blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AQP-3; GIL

Description (Vector)

AQP3 encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.

Gene ID

360

Gene Name (Vector)

aquaporin 3 (Gill blood group)

Gene Symbol

AQP3

HGNC ID

HGNC:636

ORF Size (aa)

879

ORF Size (bp)

879 bp

RefSeq ID

NM_004925

RefSeq Synonyms

NM_004925, NM_001318144, BC013566,

Species

human

UniGene ID

Hs.234642

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.