human APOH shRNA silencing Adenovirus

Name 
Ad-h-APOH-shRNA
Cat No 
shADV-201201
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human APOH.

shADV-201201
Ad-h-APOH-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human APOH (apolipoprotein H). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
activated protein C-binding protein; anticardiolipin cofactor; APC inhibitor; apo-H; Apolipoprotein H; apolipoprotein H (beta-2-glycoprotein I); B2G1; B2GP1; B2GPI; beta(2)GPI; beta-2-glycoprotein 1; Beta-2-glycoprotein I; BG; epididymis secretory sperm binding protein
Description (eCommerce)
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq].
Description (Vector)
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
Gene ID
350
Gene Name (eCommerce)
apolipoprotein H
Gene Name (Vector)
apolipoprotein H
Gene Symbol
APOH
HGNC ID
HGNC:616
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1038
ORF Size (bp)
1038 bp
Protein Name (eCommerce)
Beta-2-glycoprotein 1
RefSeq ID
NM_000042
RefSeq Synonyms
NM_000042, BC026283, BC020703,
Research Areas
Angiogenesis,Apoptosis,Cardiovascular,Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,metabolism,signal_transduction
Species
human
Target Sentence
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq].
UniGene ID
Hs.445358
UniProt ID (eCommerce)
P02749

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.