human APLNR shRNA silencing Adenovirus

Name
Ad-h-APLNR-shRNA

Cat No
shADV-201157

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human APLNR.

shADV-201157

Ad-h-APLNR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human APLNR (apelin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AGTRL1; APJ; APJR; HG11

Description (Vector)

APLNR encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Gene ID

187

Gene Name (Vector)

apelin receptor

Gene Symbol

APLNR

HGNC ID

HGNC:339

ORF Size (aa)

1143

ORF Size (bp)

1143 bp

RefSeq ID

NM_005161

RefSeq Synonyms

NM_005161, BC032688,

Species

human

UniGene ID

Hs.438311

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.