human AP1G1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AP1G1.
shADV-201074
Ad-h-AP1G1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AP1G1 (adaptor related protein complex 1 gamma 1 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
adapter-related protein complex 1 subunit gamma-1; adaptor protein complex AP-1 subunit gamma-1; adaptor related protein complex 1 gamma 1 subunit; Adaptor-related protein complex 1 subunit gamma-1; ADTG; AP-1 complex subunit gamma-1; CLAPG1; clathrin assembly protein complex 1 gamma large chain; clathrin assembly protein complex 1 gamma-1 large chain; clathrin-associated/assembly/adaptor protein, large, gamma 1; gamma adaptin; gamma1-adaptin; golgi adaptor HA1/AP1 adaptin gamma subunit; golgi adaptor HA1/AP1 adaptin subunit gamma-1; testicular tissue protein Li 21
Description (eCommerce)
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles [taken from NCBI Entrez Gene (Gene ID: 164)].
Description (Vector)
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
164
Gene Name (eCommerce)
adaptor related protein complex 1 subunit gamma 1
Gene Name (Vector)
adaptor related protein complex 1 gamma 1 subunit
Gene Symbol
AP1G1
HGNC ID
HGNC:555
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2478
ORF Size (bp)
2478 bp
Protein Name (eCommerce)
AP-1 complex subunit gamma-1
RefSeq ID
NM_001128
RefSeq Synonyms
NM_001128, NM_001030007, BC036283,
Research Areas
Antigen Processing and Presentation,Golgi Apparatus,Host-Virus Interactions,Immunology,Lysosome,Transport
Research Areas (Faceted)
immunology,cell_biology,infectious_disease
Species
human
Target Sentence
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles [taken from NCBI Entrez Gene (Gene ID: 164)].
UniGene ID
Hs.461253
UniProt ID (eCommerce)
O43747
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.