human ANGPT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ANGPT1.
shADV-200906
Ad-h-ANGPT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ANGPT1 (angiopoietin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGP1; AGPT; ANG1
Description (Vector)
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
284
Gene Name (Vector)
angiopoietin 1
Gene Symbol
ANGPT1
HGNC ID
HGNC:484
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
RefSeq ID
NM_001146
RefSeq Synonyms
NM_001314051, NM_001199859, NM_001146, BC166662, BC152419, BC152411, BC029406,
Species
human
UniGene ID
Hs.369675
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.