human ALPP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ALPP.
shADV-200814
Ad-h-ALPP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ALPP (alkaline phosphatase, placental). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALP; PALP; PLAP; PLAP-1
Description (Vector)
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Gene ID
250
Gene Name (Vector)
alkaline phosphatase, placental
Gene Symbol
ALPP
HGNC ID
HGNC:439
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_001632
RefSeq Synonyms
NM_001632, BC094743, BC068501, BC009647,
Species
human
UniGene ID
Hs.284255
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.