human AKR1C1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AKR1C1.
shADV-200681
Ad-h-AKR1C1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AKR1C1 (aldo-keto reductase family 1 member C1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB
Description (Vector)
AKR1C1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. AKR1C1 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Gene ID
1645
Gene Name (Vector)
aldo-keto reductase family 1 member C1
Gene Symbol
AKR1C1
HGNC ID
HGNC:384
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_001353
RefSeq Synonyms
NM_001353, BC040210, BC020216, BC015490,
Species
human
UniGene ID
Hs.460260
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.