human AGTPBP1 shRNA silencing Adenovirus

Name 
Ad-h-AGTPBP1-shRNA
Cat No 
shADV-200582
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human AGTPBP1.

shADV-200582
Ad-h-AGTPBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AGTPBP1 (ATP/GTP binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATP/GTP-binding protein 1; carboxypeptidase-tubulin; CCP1; cytosolic carboxypeptidase 1; nervous system nuclear protein induced by axotomy protein 1 homolog; NNA1; soluble carboxypeptidase; tubulinyl-Tyr carboxypeptidase; tyrosine carboxypeptidase
Description (eCommerce)
AGTPBP1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. AGTB1 catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins [taken from NCBI Entrez Gene (Gene ID: 23287)].
Description (Vector)
NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.(supplied by OMIM, Jul 2002)
Gene ID
23287
Gene Name (eCommerce)
ATP/GTP binding protein 1
Gene Name (Vector)
ATP/GTP binding protein 1
Gene Symbol
AGTPBP1
HGNC ID
HGNC:17258
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3561
ORF Size (bp)
3561 bp
Protein Name (eCommerce)
Cytosolic carboxypeptidase 1
RefSeq ID
NM_015239
RefSeq Synonyms
NM_015239, NM_001330701, NM_001286717, NM_001286715, BC060815,
Research Areas
Mitochondrion,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology
Species
human
Target Sentence
AGTPBP1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. AGTB1 catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins [taken from NCBI Entrez Gene (Gene ID: 23287)].
UniGene ID
Hs.494321
UniProt ID (eCommerce)
Q9UPW5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.