human ADK shRNA silencing Adenovirus

Name 
Ad-h-ADK-shRNA
Cat No 
shADV-200477
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ADK.

shADV-200477
Ad-h-ADK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADK (adenosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adenosine 5'-phosphotransferase; adenosine kinase; AK; testicular tissue protein Li 14
Description (eCommerce)
Adenosine kinase (ADK) is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents [taken from NCBI Entrez Gene (Gene ID: 132)].
Description (Vector)
ADK an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
132
Gene Name (eCommerce)
adenosine kinase
Gene Name (Vector)
adenosine kinase
Gene Symbol
ADK
HGNC ID
HGNC:257
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1038
ORF Size (bp)
1038 bp
Protein Name (eCommerce)
Adenosine kinase
RefSeq ID
NM_001123
RefSeq Synonyms
NM_006721, NM_001202450, NM_001202449, NM_001123, BC003568,
Research Areas
Immunology,Kinase/Phosphatase,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
Adenosine kinase (ADK) is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents [taken from NCBI Entrez Gene (Gene ID: 132)].
UniGene ID
Hs.656586
UniProt ID (eCommerce)
P55263

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.