human ADAMTS5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADAMTS5.
shADV-200390
Ad-h-ADAMTS5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTS5 (ADAM metallopeptidase with thrombospondin type 1 motif 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2
Description (Vector)
ADAMTS5 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.
Gene ID
11096
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 5
Gene Symbol
ADAMTS5
HGNC ID
HGNC:221
ORF Size (aa)
2793
ORF Size (bp)
2793 bp
RefSeq ID
NM_007038
RefSeq Synonyms
NM_007038, BC093777, BC093775,
Species
human
UniGene ID
Hs.58324
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.