human ADAMTS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADAMTS2.
shADV-200386
Ad-h-ADAMTS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTS2 (ADAM metallopeptidase with thrombospondin type 1 motif 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADAM-TS2; ADAMTS-2; ADAMTS-3; NPI; PC I-NP; PCI-NP; PCINP; PCPNI; PNPI
Description (Vector)
ADAMTS2 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
Gene ID
9509
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 2
Gene Symbol
ADAMTS2
HGNC ID
HGNC:218
ORF Size (aa)
3633
ORF Size (bp)
3633 bp
RefSeq ID
NM_014244
RefSeq Synonyms
NM_021599, NM_014244, BC111459,
Species
human
UniGene ID
Hs.591725
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.