human ADAM18 shRNA silencing Adenovirus

Name
Ad-h-ADAM18-shRNA

Cat No
shADV-200350

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ADAM18.

shADV-200350

Ad-h-ADAM18-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAM18 (ADAM metallopeptidase domain 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ADAM27; tMDCIII

Description (Vector)

ADAM18 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

8749

Gene Name (Vector)

ADAM metallopeptidase domain 18

Gene Symbol

ADAM18

HGNC ID

HGNC:196

ORF Size (aa)

2220

ORF Size (bp)

2220 bp

RefSeq ID

NM_014237

RefSeq Synonyms

NM_014237, NM_001320313, NM_001190956, BC121045, BC070279,

Species

human

UniGene ID

Hs.127930

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.