human ACTR1B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ACTR1B.
shADV-200309
Ad-h-ACTR1B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ACTR1B (ARP1 actin-related protein 1 homolog B, centractin beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARP1B; CTRN2; PC3
Description (Vector)
ACTR1B encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
Gene ID
10120
Gene Name (Vector)
ARP1 actin-related protein 1 homolog B, centractin beta
Gene Symbol
ACTR1B
HGNC ID
HGNC:168
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
RefSeq ID
NM_005735
RefSeq Synonyms
NM_005735, BC010090, BC006372, BC004374,
Species
human
UniGene ID
Hs.98791
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.