human ACER2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ACER2.
shADV-200187
Ad-h-ACER2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ACER2 (alkaline ceramidase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALKCDase2; ASAH3L
Description (Vector)
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 (PubMed 16940153)).(supplied by OMIM, Jul 2010)
Gene ID
340485
Gene Name (Vector)
alkaline ceramidase 2
Gene Symbol
ACER2
HGNC ID
HGNC:23675
ORF Size (aa)
681
RefSeq ID
NM_001010887
RefSeq Synonyms
NM_001010887, BC092487,
Species
human
UniGene ID
Hs.41379
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.