human ABCF1 shRNA silencing Adenovirus

Name 
Ad-h-ABCF1-shRNA
Cat No 
shADV-200091
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ABCF1.

shADV-200091
Ad-h-ABCF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ABCF1 (ATP binding cassette subfamily F member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ABC27; ABC50; ATP-binding cassette 50; ATP-binding cassette 50 (TNF-alpha stimulated); ATP-binding cassette sub-family F member 1; ATP-binding cassette, sub-family F (GCN20), member 1; TNFalpha-inducible ATP-binding protein; TNF-alpha-stimulated ABC protein
Description (eCommerce)
ATP-binding cassette sub-family F member 1 (ABCF1) is also known as ABC50 and belongs to the adenosine-triphosphate-binding cassette (ABC) family of transporters. ABC transporters are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and white. ABC50 is a member of the GCN20 subfamily. Unlike other ABC family members, ABC50 is not a membrane-spanning protein. ABC50 has been found to play a role in translation initiation and interacts with eIF2.
Description (Vector)
ABCF1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.
Gene ID
23
Gene Name (eCommerce)
ATP binding cassette subfamily F member 1
Gene Name (Vector)
ATP binding cassette subfamily F member 1
Gene Symbol
ABCF1
HGNC ID
HGNC:70
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2538
ORF Size (bp)
2538 bp
Protein Name (eCommerce)
ATP-binding cassette sub-family F member 1
RefSeq ID
NM_001090
RefSeq Synonyms
NM_001090, NM_001025091, BC112923, BC034488,
Research Areas
Cancer,Immunology,Translational Control,Transport
Research Areas (Faceted)
cancer,cell_biology,immunology,transcription_translation
Species
human
Target Sentence
ATP-binding cassette sub-family F member 1 (ABCF1) is also known as ABC50 and belongs to the adenosine-triphosphate-binding cassette (ABC) family of transporters. ABC transporters are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and white. ABC50 is a member of the GCN20 subfamily. Unlike other ABC family members, ABC50 is not a membrane-spanning protein. ABC50 has been found to play a role in translation initiation and interacts with eIF2.
UniGene ID
Hs.655285
UniProt ID (eCommerce)
Q8NE71

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.