human A1CF shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human A1CF.
shADV-200003
Ad-h-A1CF-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human A1CF (APOBEC1 complementation factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACF; ACF64; ACF65; APOBEC1CF; ASP
Description (Vector)
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene ID
29974
Gene Name (Vector)
APOBEC1 complementation factor
Gene Symbol
A1CF
ORF Size (aa)
1785
ORF Size (bp)
1785 bp
RefSeq ID
NM_138933
RefSeq Synonyms
NM_138933, NM_138932, NM_014576, NM_001198820, NM_001198819, NM_001198818, BC144196, BC130519, BC054873,
Species
human
UniGene ID
Hs.499643
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.