rat PROM1 shRNA silencing AAV

Name
AAV-r-PROM1-shRNA

Cat No
shAAV-295159

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Prom1.

shAAV-295159

AAV-r-PROM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Prom1 (prominin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD133; Prom

Description (Vector)

Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Gene ID

60357

Gene Name (Vector)

prominin 1

Gene Symbol

Prom1

ORF Size (aa)

258

ORF Size (bp)

258 bp

RefSeq ID

NM_001110137

RefSeq Synonyms

NM_021751, NM_001110137, BC126091,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.