rat ZC3H12A shRNA silencing AAV

Name 
AAV-r-ZC3H12A-shRNA
Cat No 
shAAV-295101
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Zc3h12a.

shAAV-295101
AAV-r-ZC3H12A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Zc3h12a (zinc finger CCCH type containing 12A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MCPIP-1; Reg1; RGD1306776
Description (Vector)
Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.
Gene ID
313587
Gene Name (Vector)
zinc finger CCCH type containing 12A
Gene Symbol
Zc3h12a
ORF Size (aa)
1791
ORF Size (bp)
1791 bp
RefSeq ID
NM_001077671
RefSeq Synonyms
NM_001077671, BC127516,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.