rat FKBP8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Fkbp8.
shAAV-294761
AAV-r-FKBP8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Fkbp8 (FK506 binding protein 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FKBP-8
Description (Vector)
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Gene ID
290652
Gene Name (Vector)
FK506 binding protein 8
Gene Symbol
Fkbp8
ORF Size (aa)
1212
ORF Size (bp)
1212 bp
RefSeq ID
NM_001037180
RefSeq Synonyms
NM_001037180, BC107454,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.