rat HNRPDL shRNA silencing AAV

Name
AAV-r-HNRPDL-shRNA

Cat No
shAAV-294710

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Hnrnpdl.

shAAV-294710

AAV-r-HNRPDL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Hnrnpdl (heterogeneous nuclear ribonucleoprotein D-like). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hnRNP DL; Hnrpdl

Description (Vector)

Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence.

Gene ID

305178

Gene Name (Vector)

heterogeneous nuclear ribonucleoprotein D-like

Gene Symbol

Hnrnpdl

ORF Size (aa)

969

ORF Size (bp)

969 bp

RefSeq ID

NM_001033696

RefSeq Synonyms

NM_001033696, BC104683,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.