rat LER3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Ier3.
shAAV-294483
AAV-r-LER3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Ier3 (immediate early response 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dif2; Iex1; Ler3; Prg1
Description (Vector)
IER3 may play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival.
Gene ID
294235
Gene Name (Vector)
immediate early response 3
Gene Symbol
Ier3
ORF Size (aa)
483
RefSeq ID
NM_212505
RefSeq Synonyms
NM_212505, BC099831,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.