rat KATNA1 shRNA silencing AAV

Name
AAV-r-KATNA1-shRNA

Cat No
shAAV-293983

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Katna1.

shAAV-293983

AAV-r-KATNA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Katna1 (katanin catalytic subunit A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as during disassembly of interphase microtubules at the G2-M transition. May also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body may allow their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth (By similarity).

Gene ID

292464

Gene Name (Vector)

katanin catalytic subunit A1

Gene Symbol

Katna1

ORF Size (aa)

1476

ORF Size (bp)

1476 bp

RefSeq ID

NM_001004217

RefSeq Synonyms

NM_001004217, BC097929,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.