rat PTGR1 shRNA silencing AAV

Name
AAV-r-PTGR1-shRNA

Cat No
shAAV-293537

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Ptgr1.

shAAV-293537

AAV-r-PTGR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ptgr1 (prostaglandin reductase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Dig1; Ltb4dh

Description (Vector)

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.

Gene ID

192227

Gene Name (Vector)

prostaglandin reductase 1

Gene Symbol

Ptgr1

ORF Size (aa)

990

ORF Size (bp)

990 bp

RefSeq ID

NM_138863

RefSeq Synonyms

NM_138863, BC089775,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.