rat SPG3A shRNA silencing AAV

Name
AAV-r-SPG3A-shRNA

Cat No
shAAV-293197

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Atl1.

shAAV-293197

AAV-r-SPG3A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Atl1 (atlastin GTPase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Spg3a

Description (Vector)

GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.

Gene ID

362750

Gene Name (Vector)

atlastin GTPase 1

Gene Symbol

Atl1

ORF Size (aa)

1677

ORF Size (bp)

1677 bp

RefSeq ID

NM_001009831

RefSeq Synonyms

NM_001009831, BC092645,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.