rat BDNF shRNA silencing AAV

Name 
AAV-r-BDNF-shRNA
Cat No 
shAAV-292605
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Bdnf.

shAAV-292605
AAV-r-BDNF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Bdnf (brain-derived neurotrophic factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
68
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Gene ID
24225
Gene Name (Vector)
brain-derived neurotrophic factor
Gene Symbol
Bdnf
ORF Size (aa)
750
ORF Size (bp)
750 bp
RefSeq ID
NM_001270630
RefSeq Synonyms
NM_012513, NM_001270638, NM_001270637, NM_001270636, NM_001270635, NM_001270634, NM_001270633, NM_001270632, NM_001270631, NM_001270630, BC087634,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.