human BDNF shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BDNF.
shAAV-202083
AAV-h-BDNF-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BDNF (brain derived neurotrophic factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ANON2; BULN2
Description (Vector)
BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
Gene ID
627
Gene Name (Vector)
brain derived neurotrophic factor
Gene Symbol
BDNF
HGNC ID
HGNC:1033
ORF Size (aa)
744
ORF Size (bp)
744 bp
RefSeq ID
NM_001709
RefSeq Synonyms
NM_170735, NM_170734, NM_170733, NM_170732, NM_170731, NM_001709, NM_001143816, NM_001143814, NM_001143813, NM_001143812, NM_001143811, NM_001143810, NM_001143809, NM_001143808, NM_001143807, NM_001143806, NM_001143805, BC029795,
Species
human
UniGene ID
Hs.502182
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.