rat SIRT2 shRNA silencing AAV

Name
AAV-r-SIRT2-shRNA

Cat No
shAAV-292377

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Sirt2.

shAAV-292377

AAV-r-SIRT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Sirt2 (sirtuin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.

Gene ID

361532

Gene Name (Vector)

sirtuin 2

Gene Symbol

Sirt2

ORF Size (aa)

1053

ORF Size (bp)

1053 bp

RefSeq ID

NM_001008368

RefSeq Synonyms

NM_001008368, BC086545,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.