rat SGMS2 shRNA silencing AAV

Name
AAV-r-SGMS2-shRNA

Cat No
shAAV-292199

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Sgms2.

shAAV-292199

AAV-r-SGMS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Sgms2 (sphingomyelin synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RGD1305778; spermatin

Description (Vector)

Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Required for cell growth.

Gene ID

310849

Gene Name (Vector)

sphingomyelin synthase 2

Gene Symbol

Sgms2

ORF Size (aa)

1098

ORF Size (bp)

1098 bp

RefSeq ID

NM_001014043

RefSeq Synonyms

NM_001014043, BC085803,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.