rat C2 shRNA silencing AAV

Name
AAV-r-C2-shRNA

Cat No
shAAV-292105

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat C2.

shAAV-292105

AAV-r-C2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat C2 (complement C2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor 4b to generate the C3 or C5 convertase.

Gene ID

24231

Gene Name (Vector)

complement C2

Gene Symbol

ORF Size (aa)

2277

ORF Size (bp)

2277 bp

RefSeq ID

NM_172222

RefSeq Synonyms

NM_172222, BC070923,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.