rat GJA1 shRNA silencing AAV

Name
AAV-r-GJA1-shRNA

Cat No
shAAV-291819

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Gja1.

shAAV-291819

AAV-r-GJA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Gja1 (gap junction protein, alpha 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Cx43

Description (Vector)

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).

Gene ID

24392

Gene Name (Vector)

gap junction protein, alpha 1

Gene Symbol

Gja1

ORF Size (aa)

1149

ORF Size (bp)

1149 bp

RefSeq ID

NM_012567

RefSeq Synonyms

NM_012567, BC081842,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.