rat TARDBP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Tardbp.
shAAV-291397
AAV-r-TARDBP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Tardbp (TAR DNA binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
Gene ID
298648
Gene Name (Vector)
TAR DNA binding protein
Gene Symbol
Tardbp
ORF Size (aa)
858
ORF Size (bp)
858 bp
RefSeq ID
NM_001011979
RefSeq Synonyms
NM_001011979, BC083752,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.