rat NFATC2IP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Nfatc2ip.
shAAV-291168
AAV-r-NFATC2IP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Nfatc2ip (nuclear factor of activated T-cells 2 interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity).
Gene ID
308983
Gene Name (Vector)
nuclear factor of activated T-cells 2 interacting protein
Gene Symbol
Nfatc2ip
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_001007692
RefSeq Synonyms
NM_001007692, BC079050,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.