rat EDEM2 shRNA silencing AAV

Name
AAV-r-EDEM2-shRNA

Cat No
shAAV-291144

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Edem2.

shAAV-291144

AAV-r-EDEM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Edem2 (ER degradation enhancing alpha-mannosidase like protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RGD1303074

Description (Vector)

Involved in endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.

Gene ID

296304

Gene Name (Vector)

ER degradation enhancing alpha-mannosidase like protein 2

Gene Symbol

Edem2

ORF Size (aa)

1731

ORF Size (bp)

1731 bp

RefSeq ID

NM_001004230

RefSeq Synonyms

NM_001004230, BC079029,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.