rat HSP90AB1 shRNA silencing AAV

Name
AAV-r-HSP90AB1-shRNA

Cat No
shAAV-290875

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Hsp90ab1.

shAAV-290875

AAV-r-HSP90AB1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Hsp90ab1 (heat shock protein 90 alpha family class B member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HSP90-BETA; HSP90B; HSPC2; Hspcb

Description (Vector)

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Gene ID

301252

Gene Name (Vector)

heat shock protein 90 alpha family class B member 1

Gene Symbol

Hsp90ab1

ORF Size (aa)

2175

ORF Size (bp)

2175 bp

RefSeq ID

NM_001004082

RefSeq Synonyms

NM_001004082, BC082009,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.