rat HSP90AB1 shRNA silencing AAV

Cat. No: shAAV-290875

Availability: 6-8 weeks

Name: AAV-r-HSP90AB1-shRNA

This is an AAV expressing shRNA for silencing of Rat Hsp90ab1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Hsp90ab1
Gene Name: heat shock protein 90 alpha family class B member 1
Gene ID: 301252
Gene Synonyms: HSP90-BETA; HSP90B; HSPC2; Hspcb
ORF Size: 2175 bp
RefSeq#: NM_001004082
Gene Description: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.