rat LOC303823 shRNA silencing AAV

Name
AAV-r-LOC303823-shRNA

Cat No
shAAV-290773

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Map3k13.

shAAV-290773

AAV-r-LOC303823-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Map3k13 (mitogen-activated protein kinase kinase kinase 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Gene ID

303823

Gene Name (Vector)

mitogen-activated protein kinase kinase kinase 13

Gene Symbol

Map3k13

ORF Size (aa)

1692

ORF Size (bp)

1692 bp

RefSeq ID

NM_001013978

RefSeq Synonyms

NM_001013978, BC081976,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.