rat LIPA shRNA silencing AAV

Name
AAV-r-LIPA-shRNA

Cat No
shAAV-290708

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Lipa.

shAAV-290708

AAV-r-LIPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Lipa (lipase A, lysosomal acid type). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Chole; Chole2; LAL; Lip1

Description (Vector)

Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.

Gene ID

25055

Gene Name (Vector)

lipase A, lysosomal acid type

Gene Symbol

Lipa

ORF Size (aa)

1194

ORF Size (bp)

1194 bp

RefSeq ID

NM_012732

RefSeq Synonyms

NM_012732, BC072532,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.