rat PFN1 shRNA silencing AAV

Name
AAV-r-PFN1-shRNA

Cat No
shAAV-290525

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Pfn1.

shAAV-290525

AAV-r-PFN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Pfn1 (profilin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

100

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Gene ID

64303

Gene Name (Vector)

profilin 1

Gene Symbol

Pfn1

ORF Size (aa)

423

ORF Size (bp)

423 bp

RefSeq ID

NM_022511

RefSeq Synonyms

NM_022511, BC062405,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.