rat TRIM63 shRNA silencing AAV

Name
AAV-r-TRIM63-shRNA

Cat No
shAAV-290472

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Trim63.

shAAV-290472

AAV-r-TRIM63-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Trim63 (tripartite motif containing 63). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Murf; Murf1; Rnf28

Description (Vector)

E3 ubiquitin ligase. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.

Gene ID

140939

Gene Name (Vector)

tripartite motif containing 63

Gene Symbol

Trim63

ORF Size (aa)

1056

ORF Size (bp)

1056 bp

RefSeq ID

NM_080903

RefSeq Synonyms

NM_080903, BC061824,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.