mouse SOCS6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Socs6.
shAAV-281123
AAV-m-SOCS6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Socs6 (suppressor of cytokine signaling 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1500012M23Rik; 5830401B18Rik; AI447482; Cis4; Cish4; HSPC060; SOCS-4; SOCS-6; Socs4; SSI4; STAI4; STATI4
Description (Vector)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Gene ID
54607
Gene Name (Vector)
suppressor of cytokine signaling 6
Gene Symbol
Socs6
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_018821
RefSeq Synonyms
NM_018821, BC094443, BC085245, BC017597,
Species
mouse
UniGene ID
Mm.414331
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.