mouse HELLS shRNA silencing AAV

Name 
AAV-m-HELLS-shRNA
Cat No 
shAAV-280800
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Hells.

shAAV-280800
AAV-m-HELLS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hells (helicase, lymphoid specific). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI323785; E130115I21Rik; LSH; Lysh; PASG; YFK8
Description (Vector)
Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity).
Gene ID
15201
Gene Name (Vector)
helicase, lymphoid specific
Gene Symbol
Hells
ORF Size (aa)
2466
ORF Size (bp)
2466 bp
RefSeq ID
NM_008234
RefSeq Synonyms
NM_008234, BC100394,
Species
mouse
UniGene ID
Mm.392920

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.