mouse CXCR3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cxcr3.
shAAV-280668
AAV-m-CXCR3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cxcr3 (chemokine (C-X-C motif) receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cd183; Cmkar3
Description (Vector)
Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC)|Function: Isoform 2 is a receptor for CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC). Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis|Function: Isoform 3 mediates the activity of CXCL11.
Gene ID
12766
Gene Name (Vector)
chemokine (C-X-C motif) receptor 3
Gene Symbol
Cxcr3
ORF Size (aa)
1104
ORF Size (bp)
1104 bp
RefSeq ID
NM_009910
RefSeq Synonyms
NM_009910, BC096626,
Species
mouse
UniGene ID
Mm.12876
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.