mouse ASZ1 shRNA silencing AAV

Name
AAV-m-ASZ1-shRNA

Cat No
shAAV-280558

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Asz1.

shAAV-280558

AAV-m-ASZ1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Asz1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4933400N19Rik; Gasz; ORF3

Description (Vector)

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).

Gene ID

74068

Gene Name (Vector)

ankyrin repeat, SAM and basic leucine zipper domain containing 1

Gene Symbol

Asz1

ORF Size (aa)

1428

ORF Size (bp)

1428 bp

RefSeq ID

NM_023729

RefSeq Synonyms

NM_023729, BC058859,

Species

mouse

UniGene ID

Mm.73091

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.