mouse ASTL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Astl.
shAAV-280557
AAV-m-ASTL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Astl (astacin-like metalloendopeptidase (M12 family)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
7420700F21; C87576; Sas1b
Description (Vector)
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).
Gene ID
215095
Gene Name (Vector)
astacin-like metalloendopeptidase (M12 family)
Gene Symbol
Astl
ORF Size (aa)
1308
ORF Size (bp)
1308 bp
RefSeq ID
NM_172539
RefSeq Synonyms
NM_172539, NM_001291003, BC064729,
Species
mouse
UniGene ID
Mm.31313
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.