mouse ELF4 shRNA silencing AAV

Name 
AAV-m-ELF4-shRNA
Cat No 
shAAV-279018
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Elf4.

shAAV-279018
AAV-m-ELF4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Elf4 (E74-like factor 4 (ets domain transcription factor)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AV314029; BC042423; ENSMUSG00000053512; Gm9907; Mef
Description (Vector)
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Gene ID
56501
Gene Name (Vector)
E74-like factor 4 (ets domain transcription factor)
Gene Symbol
Elf4
ORF Size (aa)
1968
ORF Size (bp)
1968 bp
RefSeq ID
NM_019680
RefSeq Synonyms
NM_019680, BC109171, BC109160,
Species
mouse
UniGene ID
Mm.36808

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.