mouse UBP1 shRNA silencing AAV

Name
AAV-m-UBP1-shRNA

Cat No
shAAV-278078

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Ubp1.

shAAV-278078

AAV-m-UBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ubp1 (upstream binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Cp2b; LBP-1a; LBP-1b; NF2d9

Description (Vector)

Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Gene ID

22221

Gene Name (Vector)

upstream binding protein 1

Gene Symbol

Ubp1

ORF Size (aa)

1515

ORF Size (bp)

1515 bp

RefSeq ID

NM_013699

RefSeq Synonyms

NM_013699, NM_001083319, BC141082, BC139828,

Species

mouse

UniGene ID

Mm.28052

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.