mouse PAX6 shRNA silencing AAV

Name 
AAV-m-PAX6-shRNA
Cat No 
shAAV-277802
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pax6.

shAAV-277802
AAV-m-PAX6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pax6 (paired box 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1500038E17Rik; AEY11; Dey; Gsfaey11; Pax-6; Sey
Description (Vector)
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
Gene ID
18508
Gene Name (Vector)
paired box 6
Gene Symbol
Pax6
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_013627
RefSeq Synonyms
NM_013627, NM_001310146, NM_001310145, NM_001310144, NM_001244202, NM_001244201, NM_001244200, NM_001244198, BC036957, BC011272,
Species
mouse
UniGene ID
Mm.3608

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.