mouse GRIK3 shRNA silencing AAV

Cat. No: shAAV-277412

Availability: 6-8 weeks

Name: AAV-m-GRIK3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Grik3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Grik3
Gene Name: glutamate receptor, ionotropic, kainate 3
Gene ID: 14807
Gene Synonyms: 9630027E11; GluK3; Glur-7; Glur7; GluR7-3
ORF Size: 2760 bp
RefSeq#: NM_001081097
Gene Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
UniGene ID: Mm.40896