mouse VEGFA shRNA silencing AAV

Name 
AAV-m-VEGFA-shRNA
Cat No 
shAAV-275992
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Vegfa.

shAAV-275992
AAV-m-VEGFA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Vegfa (vascular endothelial growth factor A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Vegf; Vpf
Description (Vector)
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Gene ID
22339
Gene Name (Vector)
vascular endothelial growth factor A
Gene Symbol
Vegfa
ORF Size (aa)
573
RefSeq ID
NM_009505
RefSeq Synonyms
NM_009505, NM_001317041, NM_001287058, NM_001287057, NM_001287056, NM_001110268, NM_001110267, NM_001110266, NM_001025257, NM_001025250, BC061468,
Species
mouse
UniGene ID
Mm.477156

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.